Larry LOO Sai Weng

Adjunct Staff

Larry LOO Sai Weng

Adjunct Lecturer

Scientist, A*STAR Singapore Institute of Food and Biotechnology Innovation

Department of Food Science & Technology

Email: Larry01@nus.edu.sg

  • MBA, Boston University, 2022 2024
  • Postgraduate Certificate in Learning and Teaching in Higher Education (PGCHE), University of London, 2020 – 2021
  • PhD in Biological Sciences, Nanyang Technological University, 2015 – 2020
  • MSc of Biological Sciences, Nanyang Technological University, 2013 – 2015
  • BSc in Biomedical Sciences, University of Bradford, 2009 – 2012 
  • Adjunct Lecturer, Department of Food Science & Technology, National University of Singapore, 2025 – Current 
  • Scientist, A*STAR Singapore Institute of Food and Biotechnology Innovation, 2023 – Current
  • Adjunct Assistant Professor, Food, Chemical and Biotechnology Cluster, Singapore Institute of Technology, 2022 – Current
  • Lecturer and Tutor I, Department of Food Science & Technology, National University of Singapore, 2022 – 2024
  • Scientist, A*STAR Institute of Bioengineering and Bioimaging, 2020 – 2023
  • Scientific Advisor, Ants Innovate, 2021-2023
  • Research Scientist, National University of Singapore (NUS), 2021 – 2023
  • Visiting Researcher, Singapore-MIT Alliance for Research and Technology, 2021 – 2023 
  • Development of genetically engineered mammalian cells for cell therapy and food purposes
  • Biomaterials scaffolds for cultivated meat production
  • Human Embryonic Stem Cells differentiation for cell therapy manufacturing 
  • Fellowship of Higher Education Academy (FHEA) United Kingdom – 2023
  • SMART Innovation Grant 2.0 (Co-Principal Investigator) – 2023
  • A*STAR Career Development Fund (Principal Investigator) – 2022
  • STEMCELL Technologies travel award – 2017
  • First Prize, NTU-Quintiles Challenge – 2016
  • Most Original Idea Prize, A*STAR-P&G 1st Singapore Biotechnology Young Entrepreneur Scheme (YES) Competition – 2016
  • A*STAR Graduate Scholarship (PhD)A*STAR Graduate Scholarship (PhD) – 2015 

Ad-hoc reviewer for Nature Food

Zhou H*, Loo LSW*, Ong FYT, Lou X, Wang J, Myint MK, Thong A, Seow DCS, Wibowo M, Ng S, Lv Y, Kwang LG, Bennie RZ, Pang KT, Dobson RCJ, Domigan LJ, Kanagasundaram Y, Yu H. Cost-effective production of meaty aroma from porcine cells for hybrid cultivated meat.Food Chem. 2025 Jan 20;473:142946. doi: 10.1016/j.foodchem.2025.142946. Epub ahead of print. PMID: 39864181. *Co-first author* 

Bennie RZ, Ogilvie OJ, Loo LSW, Zhou H, Ng SK, Jin A, Trlin HJF, Wan A, Yu H, Domigan LJ, Dobson RCJ. A risk-based approach can guide safe cell line development and cell banking for scaled-up cultivated meat production. Nat Food. 2025 Jan;6(1):25-30. doi: 10.1038/s43016-024-01085-9. Epub 2025 Jan 3. PMID: 39753758. 

Pang, K.T*., Loo, L.S.W*., Chia, S. et al. Insight into muscle stem cell regeneration and mechanobiology. Stem Cell Res Ther 14, 129 (2023). https://doi.org/10.1186/s13287-023-03363-y *Co-first author* 

Lau HH, Amirruddin NS, Loo LSW, Chan JW, Iich E, Krishnan VG, Hoon S, Teo AKK. FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro. iScience. 2023 Jul 3;26(8):107265. doi: 10.1016/j.isci.2023.107265. PMID: 37502260; PMCID: PMC10368912. 

Wong CJK, Tai YK, Yap JLY, Fong CHH, Loo LSW, Kukumberg M, Fröhlich J, Zhang S, Li JZ, Wang JW, Rufaihah AJ, Franco-Obregón A. Brief exposure to directionally-specific pulsed electromagnetic fields stimulates extracellular vesicle release and is antagonized by streptomycin: A potential regenerative medicine and food industry paradigm. Biomaterials. 2022 Aug;287:121658. doi: 10.1016/j.biomaterials.2022.121658. Epub 2022 Jul 6. PMID: 35841726. 

Chia S, Teo G, Tay SJ, Loo LSW, Wan C, Sim LC, Yu H, Walsh I, Pang KT. An Integrative Glycomic Approach for Quantitative Meat Species Profiling. Foods. 2022; 11(13):1952. https://doi.org/10.3390/foods11131952 

Ong S, Loo L, Pang M, Tan R, Teng Y, Lou X, Chin SK, Naik MY, Yu H. Decompartmentalisation as a simple color manipulation of plant-based marbling meat alternatives. Biomaterials. 2021 Oct;277:121107. doi: 10.1016/j. 121107. Epub 2021 Sep 3. PMID: 34507131. 

Teo AKK, Nguyen L, Gupta MK, Lau HH, Loo LSW, Jackson N, Lim CS, Mallard W, Gritsenko MA, Rinn JL, Smith RD, Qian WJ, Kulkarni RN. Defective insulin receptor signaling in hPSCs skews pluripotency and negatively perturbs neural differentiation. J Biol Chem. 2021 Jan-Jun;296:100495. doi: 10.1016/j.jbc.2021.100495. Epub 2021 Mar 3. PMID: 33667549; PMCID: PMC8050001. 

Loo, L.S.W., Soetedjo, A.A.P., Lau, H.H. et al. BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells. Cell Death Dis 11, 378 (2020). https://doi.org/10.1038/s41419-020-2589-7 

Loo LSW, Vethe H, Soetedjo AAP, Paulo JA, Jasmen J, Jackson N, Bjørlykke Y, Valdez IA, Vaudel M, Barsnes H, Gygi SP, Raeder H, Teo AKK, Kulkarni RN. Dynamic proteome profiling of human pluripotent stem cell-derived pancreatic progenitors. Stem Cells. 2020 Apr;38(4):542-555. doi: 10.1002/stem.3135. Epub 2020 Jan 22. PMID: 31828876; PMCID: PMC7289403. 

Loo LSW, Lau HH, Jasmen JB, Lim CS, Teo AKK. An arduous journey from human pluripotent stem cells to functional pancreatic β cells. Diabetes Obes Metab. 2018 Jan;20(1):3-13. doi: 10.1111/dom.12996. Epub 2017 Jun 7. PMID: 28474496. 

Lau HH, Ng NHJ, Loo LSW, Jasmen JB, Teo AKK. The molecular functions of hepatocyte nuclear factors – In and beyond the liver. J Hepatol. 2018 May;68(5):1033-1048. doi: 10.1016/j.jhep.2017.11.026. Epub 2017 Nov 24. PMID: 29175243. 

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